Lawrence A. Crum, Ph.D.
Principal Physicist and Chair of the Department of Acoustics and Electromagnetics
Applied Physics Laboratory
Research Professor of Bioengineering and Electrical Engineering
University of Washington
Seattle, WA
When High Intensity Focused Ultrasound (HIFU) at megahertz
frequencies and kilowatt intensities is applied to animal
tissue, absorption can result in focal temperatures that
exceed 70 oC within a few seconds. These high temperatures
result in protein denaturization and coagulative necrosis,
with the result that bleeding in the capillary bed and within
small vessels is rapidly terminated. Additionally, if HIFU is
applied to tears or cuts in large vessels, a combination of
acoustic streaming and sound absorption can lead to acoustic
hemostasis also in a few seconds. We have examined the application
of this phenomenon to trauma care and non-invasive surgery and
find that it has many promising attributes. We shall present a
general review of our work in this area as well as our most
recent results and their clinical implications.
Biography
Dr. Lawrence A. Crum is currently Principal Physicist and
Chair of the Department of Acoustics and Electromagnetics
in the Applied Physics Laboratory, and Research Professor
of Bioengineering and Electrical Engineering at the University
of Washington. He has held previous positions at Harvard
University, the U. S. Naval Academy and the University of
Mississippi, where he was F. A. P. Barnard Distinguished
Professor of Physics and Director of the National Center
for Physical Acoustics. He has published over 180 articles
in professional journals, presented over 200 papers at
professional meetings, and holds an honorary doctorate from
the Universite Libre de Bruxelles. He is Past President of
the Acoustical Society of America and current President of
the Board of the International Commission for Acoustics. In
June of 2000, he was awarded the Helmholtz-Rayleigh
Interdisciplinary Silver Medal of the Acoustical Society of
America.
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