Bioacoustics Research Lab
University of Illinois at Urbana-Champaign | Department of Electrical and Computer Engineering | Department of Bioengineering
Department of Statistics | Coordinated Science Laboratory | Beckman Institute | Food Science and Human Nutrition | Division of Nutritional Sciences | College of Engineering
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William D. O'Brien, Jr. publications:

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BRL Abstracts Database

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Title Ultrasound in the study of atherosclerosis.
Author Strandness DE Jr.
Journal Ultrasound Med Biol
Volume
Year 1986
Abstract Ultrasound has come to play an increasingly important role in investigating atherosclerosis. The simple, continuous wave directional devices may be used to measure limb blood pressure and assess velocity patterns from accessible arteries. The recent combined B-mode and pulsed Doppler systems are being used regularly to study the carotid bifurcation in the neck. With improvements in image resolution, Doppler technology and signal processing methods, it is now feasible to evaluate the morphology of the plaque and accurately predict the degree of stenosis by the recorded velocity changes in the residual lumen. By the development of transducers of low transmitting frequency (less than 5 mHz), it is now possible to evaluate arteries at greater depth such as the renal and mesenteric vessels. Duplex scanning promises to become the definitive, noninvasive method of assessing both the anatomy and flow characteristics of all major arteries outside the thorax and skull that are common sites for the development of atherosclerosis.


Title Ultrasound in the transcutaneous assessment of blood flow.
Author Yao ST.
Journal BR J Hosp Med
Volume
Year 1972
Abstract No abstract available.


Title Ultrasound in the treatment of sprained ankles.
Author Makuloluwe RT, Mouzas GL.
Journal Practitioner
Volume
Year 1977
Abstract No abstract available.


Title Ultrasound in treatment of painful shouldeers in patients with hemiplegia.
Author Inaba MK, Piorkowski M.
Journal Phys Ther
Volume
Year 1972
Abstract A study of thirty-three patients was conducted to test the hypothesis that ultrasound reduces pain in the painful shoulders of patients with hemiplegia. Three types of treatment were given for a four-week period: range-of-motion exercise and positioning; range-of-motion exercise, positioning, and ultrasound; or range-of-motion exercise, positioning, and mock ultrasound. No significant difference was found among treatments in reduction of pain as measured by change in range of motion.


Title Ultrasound induced cavitation and sonochemical yields.
Author Gong C, Hart DP.
Journal J Acoust Soc Am
Volume
Year 1998
Abstract The introduction of a strong acoustic field to an aqueous solution results in the generation of cavitation microbubbles. The growth and collapse of these microbubbles focuses and transfers energy from the macroscale (acoustic wave) to the microscale (vapor inside the bubbles) producing extremely high localized pressures and temperatures. This unique energy focusing process generates highly reactive free radicals that have been observed to significantly enhance chemical processing. This paper presents a model that combines the dynamics of bubble collapse with the chemical composition and heat transfer are assessed and compared with previous theoretical and experimental studies. Results from this model are used to explain unusual experimentally observed sonochemical phenomena.


Title Ultrasound induced changes in the carbohydrate metabolism of mouse.
Author Mythili B.
Journal Thesis(PhD): Sri Krishnadevaraya Univ
Volume
Year 1993
Abstract No abstract available. Have synopsis only.


Title Ultrasound induced damages and time bound recovery in mouse liver.
Author Kumar RPS, Raju GS.
Journal Indian J Exp Biol
Volume
Year 1989
Abstract Therapeutic ultrasound at 875 kHz at 10 and 15 W/cm2 intensity induced extensive damages in the liver of mouse. Total exposure of 5 min was spread over 5 days. Aqueous medium was avoided by coupling the transducer directly to the skin surface. Mild to extensive damages were noted. Complete distortion of hepatocellular architecture was noted in 15 W irradiated mice. However, there was almost complete recovery by 10th day following the last exposure.


Title Ultrasound induced protein synthesis as a result of membrane damage.
Author Ross P, Edmonds PD.
Journal Proc Twenty-eighth Annu Meet AIUM - New York
Volume
Year 1983
Abstract No abstract available.


Title Ultrasound integrated backscatter tissue characterization of remote myocardial infarction in human subjects.
Author Vered Z, Mohr GA, Barzilai B, Gessler CJ Jr, Wickline SA, Wear KA, Shoup TA, Weiss AN, Sobel BE, Miller JG, Perez JE.
Journal J Am Coll Cardiol
Volume
Year 1989
Abstract To determine whether quantitative ultrasound tissue characterization differentiates normal myocardial regions from segments of remote infarction, 32 consecutive patients with a diagnosis of previous myocardial infarction were evaluated. Images were obtained in real time with a modified two-dimensional ultrasound system capable of providing continuous signals in proportion to the logarithm of integrated backscatter along each A line. In 15 patients, adequate parasternal long-axis images that delineated both normal and infarct segments were obtained with standard time-gain compensation. Image data were analyzed to yield both magnitude and delay (electrocardiographic R wave to nadir normalized for the QT interval) of the cyclic variation of backscatter. Cyclic variation was present in 55 of 56 normal myocardial sites, averaging (mean +/- SEM) 3.2 +/- 0.2 dB in magnitude and exhibiting a mean normalized delay of 0.87 +/- 0.03. The magnitude of cyclic variation in infarct segments was significantly reduced to 1.1 +/- 0.2 dB (42 sites), and the delay was markedly increased to 1.47 +/- 0.12 (21 sites) (p less than 0.0001 for both). In 20 of 42 infarct sites, no cyclic variation was detectable. Thus, ultrasound tissue characterization quantitatively differentiated infarct segments from normal myocardium in patients with remote myocardial infarction.


Title Ultrasound intensity and contractile characteristics of rat isolated papillary muscle.
Author Forester GV, Roy OZ, Mortimer AJ.
Journal Ultrasound Med Biol
Volume
Year 1985
Abstract The effect of graded intensities of continuous wave ultrasound on the contractile performance of isolated papillary muscle of rat was tested. Under isometric conditions rat left ventricular papillary muscles (n = 48) were electrically stimulated to contract at rates of 30, 60, 120 and 240 beats per minute. Muscles were perfused with a Tyrode solution at 30 degrees C under normoxic conditions. Ultrasound at intensities of 0.25, 0.50, 1.0 and 2.0 W/cm2 spatial average temporal average (SATA) at 963 kHz was applied to the muscles while recording muscle contractile characteristics. The analog data were digitized and stored on disk for analysis by computer. This revealed a significant (p less than 0.001) increase in peak developed force (F), peak rate of force development (+dF/dt) and peak rate of myocardial relaxation (-dF/dt) that was linearly related to ultrasound intensity. The muscles were more sensitive to ultrasound at 240 contractions per minute. Resting force was significantly decreased by ultrasound. Although bath temperature increased according to the ultrasound intensity, control studies in papillary muscles (n = 24) on the correlation between contractile parameters and temperature revealed that bulk heating could not account for the positive inotropic action with ultrasound. These data confirm the inotropic effect of continuous wave ultrasound on myocardial tissue and point to the possibility of applying this phenomenon therapeutically.


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