Bioacoustics Research Lab
University of Illinois at Urbana-Champaign | Department of Electrical and Computer Engineering | Department of Bioengineering
Department of Statistics | Coordinated Science Laboratory | Beckman Institute | Food Science and Human Nutrition | Division of Nutritional Sciences | College of Engineering
 Friday, March 29th, 2024
BRL Home
About BRL
Publications
Projects
People
History
Facilities
Abstracts Database
Seminars
Downloads
Archives
Bioengineering Research Partnership
William D. O'Brien, Jr. publications:

Michael L. Oelze publications:

Aiguo Han publications:

BRL Abstracts Database

Search - a quick way to search the entire Abstracts Database.
 
Advanced Search - search specific fields within the Abstracts Database.
Title
Author
Journal
Volume
Year
Abstract Text
Sort by:     Title     Author     Journal     Year
Number of records to return:     10     20     30     50

Your search for ultrasound produced 3296 results.

Page 297 out of 330

Title Ultrasonic toxicity study.
Author Fry FJ, Erdmann WA, Johnson LK, Baird AI.
Journal Ultrasound Med Biol
Volume
Year 1978
Abstract Ultrasound in a delivery format similar to that used clinically in pulse echo diagnostic techniques (1 MHz frequency range, 1000 Hz pulse repetition frequency-peak spatial and temporal intensities and pulse width are larger than those used clinically) has been applied to the male mouse testicles, non-pregnant female mouse ovaries, and pregnant mouse uterus at day 8 of gestation. The time average spatial peak intensity for a 20 sec irradiation period at each matrix site for onset of adult mortality in the males and non-pregnant females is essentially 70 W/cm(^2). These data are for a focused beam having a 6 dB beam width of 2 mm. For the pregnant animals, adult mortality begins at 23 W/cm(^2). Significant changes in litter size occur for similar intensity levels. When anomalies which occur in controls are significantly increased for irradiated animals (a striking feature of this study is the almost total lack of appearance of anomalies in irradiated animals which are not present in controls), this increased incidence is not always presented in a unidirectional manner as a function of increasing average intensity. As the average intensity levels are increased in grades to 180 W/cm(^2) there is generally an increased incidence of a given bioeffect. There are, however, some notable exceptions to this generalization. When a 6 dB beam width of 4 mm is used with the pregnant animals the adult mortality begins at 8 W/cm(^2).


Title Ultrasonic treatment of Chinese hamster cells at high intensities and long exposure times.
Author Moore JL, Coakley WT.
Journal Br J Radiol
Volume
Year 1977
Abstract Monolayers of single Chinese hamster cells growing on 0.036 mm Melinex film in specially constructed irradiation vessels were treated to continuous 990.5 kHz focused ultrasound. After treatment, cells were incubated until they formed small microcolonies (48 h) or until confluent growth was obtained (96 h). Damage was assessed by scoring a focal area of 5 mm2 for a reduction in colony number or multiplcity after three generations or for a cell-free area after seven generations. The results showed that mammalian cells withstood up to 30 times greater intensities and up to 1000 times higher exposure times than any treatments shown to produce pathological lesions in mammalian tissues. When damage was observed it was generally associated with the production of cavitation events. A non-cavitation or non-thermal effect leading to cell death was not demonstrated.


Title Ultrasonic treatment of experimental animal tumours.
Author Kremkau FW.
Journal Br J Cancer Suppl
Volume
Year 1982
Abstract Studies on the effects of ultrasound on several solid tumours in experimental animals have indicated that tumour growth rates can be reduced. These data are generally consistent with a thermal mechanism of action. Application of combined ultrasound and X-irradiation have shown that with some experimental animal tumours the radiation dose required to locally control 50% of the tumours can be reduced by ultrasound. These results were also consistent with a thermal.mechanism of action hypothesis. Fractionated X-irradiation was not enhanced as much as single dose. Pulsing the ultrasound with the same time-average intensity resulted in the same radiosensitivity enhancement. The combined effects of ultrasound and cancer chemotherapy drugs have been studied in mouse leukaemia. The treatment was applied in vitro with cells in suspension. Subsequent to treatment, the cells were inoculated into host mice and survival was monitored. Cytotoxic action of 5 of 10 drugs studied was enhanced by ultrasound. A thermal.mechanism of action apparently was not involved. Cavitation in the suspension probably played a role in the cytotoxic enhancement. Experimental data are consistent with the concept that ultrasound causes rapidly reversible cell damage which, in the presence of cytotoxic drugs, is not so readily reversed and results in significant loss of lethal potential of the malignant cells to the host.


Title Ultrasonic treatment of glaucoma.
Author Colemon DJ, Silverman RH, Yablonski ME, Harmon GK, Lucas BC.
Journal Book Chapter
Volume
Year 1989
Abstract High intensity focused ultrasound is a modality that has been introduced recently for the treatment of glaucoma, particularly when medical therapy has failed and other therapies are not judged applicable or have been of limited value. All conventional glaucoma therapies are not judged applicable or have been of limited value. All conventional glaucoma therapies have some advantages and many disadvantages. Surgery may require general anesthesia and may not always be successful, particularly in uveitis and in cases of neovascular and aphakic glaucoma. Laser trabeculoplasty is not always applicable, particularly in the treatment of secondary and closed angle glaucoma, and repetition may elevate the intraocular pressure rather than decrease it. Cyclocryotherapy is associated with many complications and may result in considerable postoperative pain.


Title Ultrasonic treatment of tumors--II. Moderate hyperthermia.
Author Child SZ, Vives B, Fridd CW, Hare JD, Linke CA, Davis HT, Carstensen EL.
Journal Ultrasound Med Biol
Volume
Year 1980
Abstract Ultrasonically induced hyperthermia (44-45 C for 10 min) and surgical excision were used in the treatment of hamster fibrosarcomas. Both pulsed and continuous wave 3 MHz radiation was used. Rates of metastasis and effectiveness in eliminating the primary tumor were approximately equal with the two methods of treatment.


Title Ultrasonic treatment of tumors-III: High intensity, low frequency exposures.
Author Child SZ, Vives B, Smachlo K, Fridd CW, Hare JD, Linke CA, Davis HT, Carstensen EL.
Journal Ultrasound Med Biol
Volume
Year 1982
Abstract Hamster fibrosarcomas were exposed to 1.06 MHz ultrasound at intensities of 90 W/cm(^2) in a pulse mode (0.1 sec on, 0.9 sec off) to avoid excessive heating. Tumor temperatures ranged from 19 to 30?C during these exposures. The treatment had no apparent effect on the rate of growth of the primary tumor or on the rate of metastasis.


Title Ultrasonic treatment of tumors: I. Absence of metastases following treatment of a hamster fibrosarcoma.
Author Smachlo K, Fridd CW, Child SZ, Hare JD, Linke CA, Carstensen EL.
Journal Ultrasound Med Biol
Volume
Year 1979
Abstract The rate of metastasis has been compared for a hamster fibrosarcoma line treated either with ultrasound or by surgical excision. Continuous wave, 5 MHz ultrasound at 3 W/sq cm for 6-8 min brought tumor temperatures to 60-70 C. The animals were observed over a period of 12 weeks. The ultrasound treatment effectively eradicated the local tumor. There was no indication of induction of metastasis by the treatment.


Title Ultrasonic velocimetry of biological compounds.
Author Sarvazyan AP.
Journal Mol Biol
Volume
Year 1983
Abstract Ultrasonic velocimetry is a recently developed acoustic method of investigating the structural characteristics and hydration of biological compounds in solution, and of studying intermolecular interactions, conformational transitions of biopolymers, and the kinetics of biochemical processes. Ultrasonic velocimetry owes its development to the appearance of new precise methods of measuring ultrasound velocity in small volumes of liquids (<1 ml) with a solution of about 10(exp)(-4)%. The basic concepts of ultrasonic velocimetry are discussed, and the relation between the measurable acoustic quantities and the properties of the investigated objects is analyzed. The topics discussed include the application of ultrasonic velocimetry to the investigation of conformational transitions of biopolymers accompanied by a change in accessibility of the polymer chain to the solvent, determination of the size and compressibility of the hydration shells of particular atomic groups of biological compounds, the investigation of binding of low-molecular-weight ligands by macromolecules, and several other problems of molecular biology.


Title Ultrasonic velocimetry of biological compounds.
Author Sarvazyan AP.
Journal Mol Biol
Volume
Year 1983
Abstract Ultrasonic velocimetry is a recently developed acoustic method of investigating the structural characteristics and hydration of biological compounds in solution, and of studying intermolecular interactions, conformational transitions of biopolymers, and the kinetics of biochemical processes. Ultrasonic velocimetry owes its development to the appearance of new precise methods of measuring ultrasound velocity in small volumes of liquids (<1 ml) with a solution of about 10(exp)(-4)%. The basic concepts of ultrasonic velocimetry are discussed, and the relation between the measurable acoustic quantities and the properties of the investigated objects is analyzed. The topics discussed include the application of ultrasonic velocimetry to the investigation of conformational transitions of biopolymers accompanied by a change in accessibility of the polymer chain to the solvent, determination of the size and compressibility of the hydration shells of particular atomic groups of biological compounds, the investigation of binding of low-molecular-weight ligands by macromolecules, and several other problems of molecular biology.


Title Ultrasonic velocity spatial distribution analysis of biological materials with the scanning laser acoustic microscope.
Author Embree PM, Foster SG, Bright G, O'Brien WD Jr.
Journal Proc Thirteenth Int Symp Acoust Imaging - Minneapolis
Volume
Year 1983
Abstract The fundamental examination of biological tissue with ultrasound can lead to important diagnostic capabilities. In order to quantify tissue characteristics with ultrasound, the ultrasonic propagation properties of normal and pathological tissues must be characterized and cataloged. An important ultrasonic property is the speed of sound for characterizing tissue. The scanning laser acoustic microscope is used to measure the spatial variation of the speed of sound in tissue, thereby providing a quantitative ultrasonic parameter for tissue characterization.


Page 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 | 144 | 145 | 146 | 147 | 148 | 149 | 150 | 151 | 152 | 153 | 154 | 155 | 156 | 157 | 158 | 159 | 160 | 161 | 162 | 163 | 164 | 165 | 166 | 167 | 168 | 169 | 170 | 171 | 172 | 173 | 174 | 175 | 176 | 177 | 178 | 179 | 180 | 181 | 182 | 183 | 184 | 185 | 186 | 187 | 188 | 189 | 190 | 191 | 192 | 193 | 194 | 195 | 196 | 197 | 198 | 199 | 200 | 201 | 202 | 203 | 204 | 205 | 206 | 207 | 208 | 209 | 210 | 211 | 212 | 213 | 214 | 215 | 216 | 217 | 218 | 219 | 220 | 221 | 222 | 223 | 224 | 225 | 226 | 227 | 228 | 229 | 230 | 231 | 232 | 233 | 234 | 235 | 236 | 237 | 238 | 239 | 240 | 241 | 242 | 243 | 244 | 245 | 246 | 247 | 248 | 249 | 250 | 251 | 252 | 253 | 254 | 255 | 256 | 257 | 258 | 259 | 260 | 261 | 262 | 263 | 264 | 265 | 266 | 267 | 268 | 269 | 270 | 271 | 272 | 273 | 274 | 275 | 276 | 277 | 278 | 279 | 280 | 281 | 282 | 283 | 284 | 285 | 286 | 287 | 288 | 289 | 290 | 291 | 292 | 293 | 294 | 295 | 296 | 297 | 298 | 299 | 300 | 301 | 302 | 303 | 304 | 305 | 306 | 307 | 308 | 309 | 310 | 311 | 312 | 313 | 314 | 315 | 316 | 317 | 318 | 319 | 320 | 321 | 322 | 323 | 324 | 325 | 326 | 327 | 328 | 329 | 330