Bioacoustics Research Lab
University of Illinois at Urbana-Champaign | Department of Electrical and Computer Engineering | Department of Bioengineering
Department of Statistics | Coordinated Science Laboratory | Beckman Institute | Food Science and Human Nutrition | Division of Nutritional Sciences | College of Engineering
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Your search for ultrasound produced 3296 results.

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Title The effect of scanning speed on temperature and equivalent thermal exposure distributions during ultrasound hyperthermia in vivo.
Author Hynynen K, Roemer R, Moros E, Johnson C, Anhalt D.
Journal IEEE Trans Microw Theory Tech
Volume
Year 1986
Abstract Experiments on eight dogs using scanned, focused ultrasound to heat thighs in vivo were performed using extensive thermometry (56 thermocouples) to measure the temperahrre fields produced. The effects of scanning speed, bIood perfusion, and applied power level are investigated. The results show that the temperature fluctuations present at low scanning speeds can significantly enhance the equivalent thermal exposure of the tissue. A theoretical analysis substantiates the major experimental results.


Title The effect of solvation on the ultrasonic absorption of bovine serum albumin solutions.
Author Evans JA, Barnes C, Lewis TJ.
Journal Ultrasound Med Biol
Volume
Year 1988
Abstract The role of solvation and structural equilibria in determining the ultrasonic absorption of aqueous solutions of bovine serum albumin has been investigated using chemical agents to denature the protein in solution. The agents used were methanol, ammonium sulphate, and guanidine hydrochloride. Two different techniques of measurement were used to cover the frequency range 200 kHz to 30 MHz. The results show that only guanidine hydrochloride produces a significant change in ultrasonic absorption even though the other agents were used at concentrations close to those which would produce protein precipitation. The conclusion is that in the above frequency range structural and solvation-related equilibria are unimportant and only perturbation of proton-transfer equilibria associated with the protein amino acid residues leads to the bulk of the ultrasonic absorption.


Title The effect of therapeutic ultrasound on angiogenesis.
Author Young SR, Dyson M.
Journal Ultrasound Med Biol
Volume
Year 1990
Abstract The effect of therapeutic ultrasound on the formation of new blood vessels in.full-thickness excised lesions in the flank skin of adult rats was assessed.quantitatively using microfocal x-ray techniques. Wounds were either sham-treated.(control group) or exposed to ultrasound for 5 min daily at an intensity of 0.1 W/cm2.SATA (frequency either 0.75 MHz or 3.0 MHz). By 5 days after injury there were.more blood vessels in equivalent regions of the granulation tissue of the.ultrasound-treated wounds than in the control wounds. This suggested that the.ultrasound-treated wounds were at a more advanced stage in the repair process. By 7.days after injury there was no significant difference in blood vessel number between.the three groups.


Title The effect of therapeutic ultrasound on calcium uptake in fibroblasts.
Author Mortimer AJ, Dyson M.
Journal Ultrasound Med Biol
Volume
Year 1988
Abstract The effect of therapeutic ultrasound on calcium uptake by embryonic chick 3T3 fibroblasts has been studied using calcium-45 radiotracer techniques. Cells were treated while suspended in culture medium at 36°C at intensities from 0.25 W/cm2 SPPA to 1.5 W/cm2 SPPA (1 MHz, pulsed 2 ms on:8 ms off) and for exposure times from 1 min to 20 min. Ultrasound treatment was found to increase calcium uptake for SPPA intensities from 0.5 to 1.0 W/cm2 SPPA, with a maximum increase of 18% after a 5 min exposure. Calcium uptake also increased with increasing exposure time. Measurements performed up to 20 min after treatment showed that the cell was able to reduce this calcium influx, indicating that the membrane did not suffer irreparable damage as a result of the ultrasound exposure.


Title The effect of therapeutic ultrasound on electrophysiological parameters of frog skin.
Author Dinno MA, Crum LA, Wu J.
Journal Ultrasound Med Biol
Volume
Year 1989
Abstract There are two groups of mechanisms through which ultrasound can affect biological systems, those of thermal origin and others of nonthermal origin. Since in almost every therapeutic application of ultrasound, movement of ions across cellular membranes is involved, it becomes important to study the effect of ultrasound on active and passive ionic conductance. In order to differentiate between thermal and nonthermal effects, a study was conducted on model systems in which the effect of temperature is known. The well-known sodium transporting epithelium, the epidermis of abdominal frog skin, was investigated and the effect of therapeutic ultrasound on its electrophysiological properties was determined. It was found that under open circuit conditions, irradiation of the skin with 1 MHz cw (60-480 mW/cm2) ultrasound caused a significant decrease (5-50%, depending on the applied power) in the transepithelial potential and resistance at room temperature (20-22 degrees C). Under short circuit conditions, also at room temperature, there was an increase in total ionic conductance (20-250%, depending on the applied power) and a decrease in the net actively transported current, measured as the short circuit current. These effects are reversible within the range of powers used. Furthermore, it was found that the magnitude of the observed changes was strongly dependent on the perfusion rate and the gas content of the bathing medium. The effect of ultrasound diminished in the presence of CO2 and was enhanced with faster perfusion rates. Pulsed ultrasound delivered at the same energy (Isata) as that of cw caused a significantly larger effect. At lower temperatures (12-14 degrees C) the effect of ultrasound was reduced. Analysis of the data reveals that the effects of ultrasound on ion transport reported here are not primarily of thermal origin but are probably due to cavitation and related effects, such as microsteaming.


Title The effect of ultrasonic cavitation on protein antigenicity.
Author Edwards JH, James CJ, Coakley WT, Brown RC.
Journal J Acoust Soc Am
Volume
Year 1976
Abstract The antigenicity and enzyme activity of dilute solutions of RNAse exposed to ultrasonic cavitation have been measured as a function of exposure time. The rate of decrease of antigenicity was one-eighth of the rate of enzyme activity loss. The implication of the results for the use of ultrasound in antigen preparation is discussed.


Title The effect of ultrasonic irradiation on the structural integrity of the inner ear labyrinth.
Author Barnett SB.
Journal Acta Otolaryngol
Volume
Year 1980
Abstract The histological appearance of the inner ear labyrinth was examined following ultrasonic irradiation of the vestibule and the cochlea in cats and guinea pigs. Directing ultrasound through the round window towards the ampulla of the superior semicircular canal produced severe balance dysfunction together with histological damage throughout the vestibular labyrinth. Cochlear damage was restricted to a small region of the basilar membrane proximal to the round window. When ultrasonic energy was directed into the cochlea cellular disruption extended over an area of at least two cochlear turns and included changes in the stria vascularis as well as to hair cells. The outer hair cells were found to be more sensitive than the inner hair cells to the damaging effects of ultrasound.


Title The effect of ultrasonics on the permeability of a living membrane to NA(22).
Author Braungart DC.
Journal Rep WADC
Volume
Year 1954
Abstract This report introduces some preliminary tests necessary to pursue research on the effects of ultrasound on living cell membranes. By means of an isotope it was possible to measure the permeability of a living cell membrane to a weak ultrasonic field. Techniques and instrumentation had to be developed. As a result of the experiments described, it has been shown that a weak ultrasonic field does increase the permeability of the living cell membrane of the amoebae in much the same way as do surface active agents, lipase and thioglycollic acid.


Title The effect of ultrasound and hyperthermia on sister chromatid exchange and division kinetics of BHK 21 C13/A3 cells.
Author Barrass N, ter Haar G, Casey G.
Journal Br J Cancer Suppl
Volume
Year 1982
Abstract No abstract available.


Title The effect of ultrasound exposure in utero on the development of the fetal mouse testis: Adult consequences.
Author Carnes KI, Hess RA, Dunn F.
Journal Ultrasound Med Biol
Volume
Year 1995
Abstract The effects of exposure in utero to 1 MHz, continuous-wave ultrasound on adult growth and testicular development in the mouse was investigated. The spatial peak temporal average intensity (ISPTA) employed ranged from 1 to 10 W/cm2, with exposure durations (t) of 200 s to 20 s. Exposures were made on days 9, 12 or 15 of gestation. Results showed an increase in postpartum deaths, an increase in the number of stillbirths, and a decrease in litter size when I2 t > or = 1125 W2 s/cm4, such that there was significant loss of pups. Birthweights of pups from nearly all dosage groups was significantly lower than that of the sham or cage control groups. Results also showed that males exposed to ultrasound in utero had decreased testis size and decreased daily sperm production ranging from 9% to 30%. This study showed that ultrasound exposure in utero is capable of disrupting fetal development and having potential subsequent effects on fertility in the adult male.


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