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BRL Abstracts Database |
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Your search for ultrasound produced 3296 results. Page 161 out of 330
| Title |
Involvement of ultrasonically induced cavitation in the production of hind limb paralysis of the mouse neonate. |
| Author |
Frizzell LA, Lee CS, Aschenbach PD, Borrelli MJ, Morimoto RS, Dunn F. |
| Journal |
J Acoust Soc Am |
| Volume |
|
| Year |
1983 |
| Abstract |
The exposure conditions which produce hind limb paralysis in 10%, 50%, and 90% of mouse neonate specimens exposed to 1-MHz ultrasound at 10 degrees C and at 1- and 16-atm hydrostatic pressure were determined for the intensity range 86-289 W/cm(^2). The change in the exposure duration for 50% of the specimens paralyzed resulting from pressurization to 16 atm was negligible at 86 and 144 W/cm(^2) but was almost a factor of 2 increase at 289 W/cm(^2). Pressurization suppressed the observed half-harmonic received signal at all intensities. These results suggest that cavitation may influence the production of the hind limb paralysis produced in the neonate at 1 atm and at 289 W/cm(^2). |
| Title |
Iodine release as an indicator of acoustic cavitation. |
| Author |
Ciaravino V, Miller MW. |
| Journal |
Proc Ultrason Symp IEEE |
| Volume |
|
| Year |
1983 |
| Abstract |
A spectrophotometric and a radioactive-label technique were used to assess acoustically induced iodine release. The exposure system was a glass test tube insonated transversely with a 1 MHz ultrasound source. The medium used for the assays was 5.0 mM sodium iodide in the presence of carbon tetrachloride. In one assay 131I was quantitated by liquid scintillation counting and in the other the optical density of the solution was monitored at 520 nm. For both techniques there was a dose dependent relationship between the percentage of iodine released and.the ultrasound intensity (1 MHz, ISp to 30 WICM2 continuous wave for one minute). Exposure of Na 131I at varying pulsed regimes (1:1 duty cycle, 60 sec - 60 msec pulse duration) and intensities (10-30 W/cm2) resulted in an increased efficiency of pulsed ultrasound to produce iodine release compared to that obtained with continuous wave exposures. Iodine release decreased with increased atmospheric pressure or increased concentrations of the radical scavenger cysteamine, thus confirming that the release was related to cavitational processes. |
| Title |
Iridoschisis: high frequency ultrasound imaging. Evidence for a genetic defect? |
| Author |
Danias J, Aslanides IM, Eichenbaum JW, Silverman RH, Reinstein DZ, Coleman DJ. |
| Journal |
Br J Ophthalmol |
| Volume |
|
| Year |
1996 |
| Abstract |
AIMS: To elucidate changes in the anatomy of the anterior chamber associated with iridoschisis, a rare form of iris atrophy, and their potential contribution to angle closure glaucoma. METHODS: Both eyes of a 71-year-old woman with bilateral iridoschisis and fibrous dysplasia and her asymptomatic 50-year-old daughter were scanned with a very high frequency (50 MHz) ultrasound system. RESULTS: The symptomatic patient exhibited diffuse changes in the iris stoma with an intact posterior iris pigmented layer in both eyes. These changes were clinically compatible with the lack of iris transillumination defects. Additionally, iris bowing with a resultant narrowing of the angle occurred. The asymptomatic daughter showed discrete, but less severe iris stromal changes. CONCLUSION: This is the first detailed study of high frequency ultrasonic imaging of the iris in iridoschisis. The observed structural changes suggest angle narrowing by forward bowing of the anterior iris stroma may be a mechanism of IOP elevation in this condition. The ultrasonic detection of iris changes in the asymptomatic daughter of the symptomatic patient and the association of iridoschisis with fibrous dysplasia suggest a possible genetic component in the pathogenesis of this condition. |
| Title |
Irradiation of plastics with focused ultrasound: A simple method for evaluation of dosage factors for neurological applications. |
| Author |
Lele PP. |
| Journal |
J Acoust Soc Am |
| Volume |
|
| Year |
1962 |
| Abstract |
Irradiation of strain‐free methacrylate with a single beam of focused ultrasound in adequate dosages results in the development of trackless focal alterations within the plastic. These alterations, easily visualized with polarized light, are egg‐shaped regions of stress and are probably thermal in origin. There is a consistent and reproducible relationship between ultrasonic dosage and the size of these “lesions,” comparable to that obtained when the brain of the cat is similarly irradiated. The use of methacrylate as a preliminary test medium permits rapid evaluation of the probable effects of varying dosage parameters as well as of the repetitive (and long term) stability of the ultrasonic output. |
| Title |
Is acoustic cavitation produced by diagnosstic ultrasound devices? |
| Author |
Crum LA. |
| Journal |
Proc Ultrason Symp IEEE |
| Volume |
|
| Year |
1987 |
| Abstract |
There is considerable evidence that acoustic cavitation can be produced in vivo by diagnostic ultrasound devices. This paper presents the available evidence and concludes that it is likely that acoustic cavitation is produced by these devices in vivo. However, because of the discrete nature of the cavitation, and the limited number of events that occur, this cavitation is unlikely to be detected or to manifest itself in terms of deleterious biological effects. |
| Title |
Is diagnostic ultrasound safe during periovulatory period? |
| Author |
Demoulin A. |
| Journal |
Res Reprod |
| Volume |
|
| Year |
1985 |
| Abstract |
No abstract available. |
| Title |
Is pulsed ultrasound mutagenic? |
| Author |
Barnett SB, Baker RSU, Barnstable S. |
| Journal |
Ultrasound |
| Volume |
|
| Year |
1982 |
| Abstract |
The possibility that microsecond pulses of 3 MHz ultrasound may interact at the cellular level, with genetic consequences, was investigated using two different endpoints. The Ames mammalian microsome test was employed to assess mutagenicity and viability in Salmonella typhimuriom bacteria, while the sister chromatid exchange frequency provided an indicator of ultrasound induced effects at the chromosome level in Chinese hamster ovary cells. |
| Title |
Is ultrasound monitoring of follicular growth harmless? |
| Author |
Demoulin A, Bologne R, Hustin J, Lambotte R. |
| Journal |
Ann N Y Acad Sci |
| Volume |
|
| Year |
1985 |
| Abstract |
Monitoring of the growth of ovarian follicles by ultrasound (US) is now frequently utilized in such procedures as hMG stimulation, artificial insemination, and in vitro fertilization. Whiel experimental studies have demonstrated that ultrasound, when used at diagnostic intensities, is not toxic for cells or tissues, until now there has been no study concerning the effect of ultrasound waves on preovulatory follicles. Using ultrasound to determine the appropriate time for artificial insemination with donor semen (AID) in 1980, we have compared the pregnancy rates in two populations of AID patients (with US versus without US). The success rate is reduced in the US-monitored group. Animal experiments confirm these results. |
| Title |
Is ultrasound safe? |
| Author |
Unknown. |
| Journal |
Parade Magazine |
| Volume |
|
| Year |
1982 |
| Abstract |
No abstract available. |
| Title |
Key factors that affect sonoporation efficiency in in vitro settings: The importance of standing wave in sonoporation. |
| Author |
Kinoshita M, Hynynen K. |
| Journal |
Biochem Biophys Res Commun |
| Volume |
|
| Year |
2007 |
| Abstract |
Ultrasound-induced intracellular drug delivery, sonoporation, is an appealing and promising technique for next generation drug delivery system. Many types of molecules, such as plasmid DNAs, siRNAs and peptides, have been demonstrated to be delivered into the cell by ultrasound with the aid of microbubbles both in vitro and in vivo. Although there are many reports on in vitro sonoporation, the efficiency of successful sonoporation and the viabilities of cells after the procedure documented in each report vary in a wide range, and the reasons for these differences are not fully understood. In this study, we have investigated how different experimental settings would affect sonoporation efficiency and cell viabilities after the procedure. Our results show that the fashion of cell culture (e.g. in suspension or in monolayer culture) and the presence of standing wave have a great impact on the overall results. These results indicate that in vitro sonoporation settings should be carefully evaluated in each experiment. The fact that standing wave is necessary to achieve high sonoporation efficiency may be a problematic issue for clinical application of sonoporation, as it may be difficult (although not impossible) to create standing wave in a human body. |
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